Sarah has worked in the field of genetics and genomics for over 20 years. She runs the Human Genomic Informatics Group that focuses on the analysis of large-scale genomic (sequencing) data in clinical cohorts. She has published ~150 papers with focus on underpinning the molecular genetic basis of human rare and common disease. She is involved in multiple projects ranging from optimisation and cleaning of digitally extracted NHS data, execution of contemporary sequencing of DNA and RNA from patient samples and integration of data from multiple ‘omic sources using machine learning approaches to inform clinical management.

Professor Ennis holds an additional role as Research Director for the Central & South Genomic Medicine Service Alliance.